Cellular Performance Comparison of Biomimetic Calcium Phosphate Coating and Alkaline-Treated Titanium Surface

Effect of Alkaline-Acid Treatment on the Biomimetic Formation of Calcium Phosphate Layers on Titanium Substrates:An In Vitro Study

Enhancing Protein Incorporation in Calcium Phosphate Coating on Titanium by Rapid Biomimetic Co-Precipitation Technique

Calcium phosphate coating (CaP) has been employed for protein delivery, but the typical direct protein adsorption on the coating led to low incorporation content and fast release of the protein from the coating. By using bovine serum albumin (BSA) as a model protein, rapid biomimetic co-precipitation between calcium phosphate and BSA was employed to control the distribution of BSA within calciu...

Preparation and Characterization of Hydroxyapatite Coating on Ti6Al4V Cylinders by Combination of Alkali-Heat Treatments and Biomimetic Method

Biomimetic method was used to apply hydroxyapatite (HA) coating onto Ti6Al4V cylinders. This process is a physicochemical method in which a substrate is soaked in a solution simulating the physiological conditions, for a period of time enough to form a desirable layer of the calcium phosphate on the substrate. In the present study, specimens were soaked in 5, 10 M solutions of NaOH at temperatu...

In vitro study on the osteogenesis enhancement effect of BMP-2 incorporated biomimetic apatite coating on titanium surfaces.

To fabricate a sustained-release delivery system of bone morphogenetic protein (BMP-2) on titanium surface, explore the effect of BMP-2 concentration on the loading/release behavior of BMP-2 and evaluate the cell compatibility of the system in vitro, pure titanium specimens were immersed into supersaturated calcium phosphate solutions (SCP) containing 4 different concentrations of BMP-2: 0, 50,...

Surface Activation of NiTi Alloy by Using Electrochemical Process for Biomimetic Deposition of Hydroxyapatite Coating (TECHNICAL NOTE)

Electrochemical depositions of calcium phosphate (Ca-P) film on NiTi alloy in concentrated simulated body flood (SBF×5) were carried out by cathodic polarization. The Ca-P layer was successfully deposited on Ni-Ti alloy substrate under 10mA/cm2 current density for 2 hours at room temperature. Then, in order to investigate the bioactivity of the pre-calcified samples, they were immersed in SBF f...